Expression of Fc and complement receptors on peripheral blood monocytes in systemic lupus erythematosus and rheumatoid arthritis

Objectives. Fcaγ and complement receptors play an important role in the interaction between immune complexes (IC) and monocytes/macrophages. Recent work has demonstrated that their relative expression on these cells may be modified by cytokines, including TNF-α and IL-4. Furthermore, cytokines may alter the expression of adhesion molecules such as ICAM-1. However, little data exist on the in vivo expression of specific Fcγ and complement...