SIFT web server: predicting effects of amino acid substitutions on proteins
Abstract
The Sorting Intolerant from Tolerant (SIFT) algorithm predicts the effect of coding variants on protein function. It was first introduced in 2001, with a corresponding website that provides users with predictions on their variants. Since its release, SIFT has become one of the standard tools for characterizing missense variation. We have updated SIFT’s genome-wide prediction tool since our last publication in 2009, and added new features to the...
Paper Details
Title
SIFT web server: predicting effects of amino acid substitutions on proteins
Published Date
Jun 9, 2012
Journal
Volume
40
Issue
W1
Pages
W452 - W457
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Notes
History