Theoretical Concepts and the Emerging Role of Taxanes in Adjuvant Therapy
Abstract
The proven benefits of adjuvant chemotherapy on disease-free and overall survival in breast cancer can be explained by concepts of cell kill. Interventions which result in greater log kill can be expected to produce improved clinical results. The application of log-kill concepts to human breast cancer growth, which appears to follow Gompertzian kinetics, suggests not only that the use of non-cross-resistant drugs is important, but that...
Paper Details
Title
Theoretical Concepts and the Emerging Role of Taxanes in Adjuvant Therapy
Published Date
Jun 1, 2001
Journal
Volume
6
Issue
90003
Pages
30 - 35
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Notes
History