An efficient protocol for palladium-catalyzed ligand-free Suzuki–Miyaura coupling in water
Abstract
An in situ generated catalytic system based on PdCl2 and sodium sulfate exhibited excellent catalytic activity in the Suzuki–Miyaura cross-coupling reactions of aryl halides with arylboronic acids at room temperature in water. A similar catalytic system can be obtained with PdCl2 and sodium chloride or sodium acetate and is equally effective in Suzuki–Miyaura cross-coupling reactions. This method offers a mild and efficient alternative to the...
Paper Details
Title
An efficient protocol for palladium-catalyzed ligand-free Suzuki–Miyaura coupling in water
Published Date
Jul 1, 2012
Journal
Volume
14
Issue
7
Pages
1873 - 1876
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