Genome engineering via TALENs and CRISPR/Cas9 systems: challenges and perspectives.
Abstract
Summary
The ability to precisely modify genome sequence and regulate gene expression patterns in a site-specific manner holds much promise in plant biotechnology. Genome-engineering technologies that enable such highly specific and efficient modification are advancing with unprecedented pace. Transcription activator-like effectors (TALEs) provide customizable DNA-binding modules designed to bind to any sequence of interest. Thus, TALEs have...
Paper Details
Title
Genome engineering via TALENs and CRISPR/Cas9 systems: challenges and perspectives.
Published Date
Oct 1, 2014
Journal
Volume
12
Issue
8
Pages
1006 - 1014
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Notes
History