Time course pathogenesis of sulphur mustard‐induced skin lesions in mouse model

Volume: 10, Issue: 4, Pages: 441 - 454
Published: Jun 4, 2012
Abstract
Sulphur mustard (SM) is a bifunctional alkylating agent that causes cutaneous blistering in humans and animals. In this study, we have presented closer views on pathogenesis of SM‐induced skin injury in a mouse model. SM diluted in acetone was applied once dermally at a dose of 5 or 10 mg/kg to Swiss albino mice. Skin was dissected out at 0, 1, 3, 6, 12, 24, 48, 72 and 168 hours, post‐SM exposure for studying histopathological changes and...
Paper Details
Title
Time course pathogenesis of sulphur mustard‐induced skin lesions in mouse model
Published Date
Jun 4, 2012
Volume
10
Issue
4
Pages
441 - 454
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