Bio-coordination of bismuth in Helicobacter pylori revealed by immobilized metal affinity chromatography
Abstract
Over 300 Bi-binding peptides from 166 proteins in H. pylori were identified by Bi-IMAC. Bi(3+) exhibits high selectivity towards peptide enriched by cysteines and histidines with dominated motif patterns of CXnC, CXnH and HXnH. Structural rationalization and functional categorization on the identified Bi-binding peptides and proteins provide an insight into the inhibitory action of bismuth...
Paper Details
Title
Bio-coordination of bismuth in Helicobacter pylori revealed by immobilized metal affinity chromatography
Published Date
Jan 1, 2015
Journal
Volume
51
Issue
92
Pages
16479 - 16482
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