Value of Claudin-4 Immunostaining in the Diagnosis of Mesothelioma

Volume: 139, Issue: 5, Pages: 611 - 619
Published: May 1, 2013
Abstract
Claudin-4 (CL-4) is a tight junction-associated protein that is expressed in most epithelial cells but absent in mesothelial cells. The purpose of this study is to evaluate the utility of CL-4 immunostaining for assisting in the differential diagnosis of mesothelioma. Sixty mesotheliomas (40 epithelioid, 10 biphasic, and 10 sarcomatoid), 185 carcinomas of different origins that can potentially be confused with mesotheliomas, 37 soft-tissue...
Paper Details
Title
Value of Claudin-4 Immunostaining in the Diagnosis of Mesothelioma
Published Date
May 1, 2013
Volume
139
Issue
5
Pages
611 - 619
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