Establishment and characterization of a human histiocytic lymphoma cell line (U‐937)

A human hematopoietic cell line (U‐937) with exceptional characteristics was derived from a patient with generalized histiocytic lymphoma. The morphology of the cell line was identical to that of the tumor cells in the pleural effusion from which the line was derived. Since Epstein‐Barr virus (EBV) carrying diploid lymphoblastoid cell lines unrelated to the tumor population often become established in vitro from non‐Burkitt lymphoma explants,...