Animal models for anti-emphysema drug discovery

Volume: 10, Issue: 4, Pages: 399 - 410
Published: Feb 23, 2015
Abstract
Emphysema is characterized by an abnormal and permanent enlargement of airspaces accompanied by destruction of their walls. Up to now, there is no cure for emphysema, and animal models may be important for new drug discovery.Herein, the authors review animal models of emphysema since the protease-antiprotease hypothesis as well as the results obtained with compounds tested in these models. Of particular importance are animal models of cigarette...
Paper Details
Title
Animal models for anti-emphysema drug discovery
Published Date
Feb 23, 2015
Volume
10
Issue
4
Pages
399 - 410
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