Prenatal Testosterone Differentiates Brain Regions Controlling Gonadotropin Release in Guinea Pigs1

Sexual differentiation of behavior and gonadotropin release in short-gestation mammalian species is affected by perinatal testosterone (T). Differentiation of dimorphic behaviors in two long-gestation species (guinea pigs and rhesus macaques) depends upon prenatal androgen exposure. The brain areas mediating gonadotropin release are not sexually differentiated in nonhuman primates, but similar information is not available for the guinea pig. To...