Antidepressant Treatment of Depression: A Metaanalysis

To carry out a metaanalysis of antidepressant studies to calculate the effect sizes for antidepressant effect in depressive disorder.A metaanalysis of all antidepressant studies that included an active comparison drug as well as placebo was used to calculate the effect size. Articles were selected from a MEDLINE search for the period January 1966 to June 1995. Forty-nine studies were included in the metaanalysis.The effect sizes for...