Photoprotective Effects of Bucillamine Against UV-induced Damage in an SKH-1 Hairless Mouse Model

UVB exposure of skin results in various biologic responses either through direct or indirect damage to DNA and non‐DNA cellular targets via the formation of free radicals, reactive oxygen species (ROS) and inflammation. Bucillamine [ N ‐(2‐mercapto‐2‐methylpropionyl)‐ l ‐cysteine] is a cysteine‐derived compound that can replenish endogenous glutathione due to its two donatable thiol groups, and functions as an antioxidant. In this study, we...