Factors affecting the success of next‐generation sequencing in cytology specimens

BACKGROUND The use of cytology specimens for next‐generation sequencing (NGS) is particularly challenging because of the unconventional substrate of smears and the often limited sample volume. An analysis of factors affecting NGS testing in cytologic samples may help to increase the frequency of successful testing. METHODS This study reviewed variables associated with all in‐house cytology cases (n = 207) that were analyzed by NGS with the Ion...