Melittin interaction with sulfated sugars and cell membranes

Published: Jan 1, 2008
Abstract
The presented work focused on an alternative mechanism of action of melittin on the cell membranes. The study using ITC reveals that melittin has a high affinity for several glycosaminoglycans (GAGs), i.e. heparan sulfate (HS), dermatan sulfate and heparin. The interaction between peptide and GAGs comprised both electrostatic and non-ionic components. Circular dichroism (CD) spectroscopy demonstrates that the binding of melittin to HS and...
Paper Details
Title
Melittin interaction with sulfated sugars and cell membranes
Published Date
Jan 1, 2008
Journal
Citation AnalysisPro
  • Scinapse’s Top 10 Citation Journals & Affiliations graph reveals the quality and authenticity of citations received by a paper.
  • Discover whether citations have been inflated due to self-citations, or if citations include institutional bias.