Adverse pulmonary vascular remodeling in the Fontan circulation

BackgroundThe Fontan circulation is a palliation for patients with a functionally univentricular heart. It is characterized by gradual attrition over time. An increase in pulmonary vascular resistance could be a key factor in the long-term failure of the Fontan circulation. In this study we aimed to identify pulmonary vascular remodeling in patients with a Fontan circulation.MethodsPulmonary vascular histomorphometric analysis and...