Prophylactic Creatine Administration Mediates Neuroprotection in Cerebral Ischemia in Mice
Abstract
Creatine mediates remarkable neuroprotection in experimental models of amyotrophic lateral sclerosis, Huntington's disease, Parkinson's disease, and traumatic brain injury. Because caspase-mediated pathways are shared functional mechanistic components in these diseases, as well as in ischemia, we evaluated the effect of creatine supplementation on an experimental stroke model. Oral creatine administration resulted in a remarkable reduction in...
Paper Details
Title
Prophylactic Creatine Administration Mediates Neuroprotection in Cerebral Ischemia in Mice
Published Date
Jun 30, 2004
Journal
Volume
24
Issue
26
Pages
5909 - 5912
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