Electrical slow waves in the mouse oviduct are dependent on extracellular and intracellular calcium sources

Spontaneous contractions of the myosalpinx are critical for oocyte transport along the oviduct. Slow waves, the electrical events that underlie myosalpinx contractions, are generated by a specialized network of pacemaker cells called oviduct interstitial cells of Cajal (ICC-OVI). The ionic basis of oviduct pacemaker activity is unknown. Intracellular recordings and Ca 2+ imaging were performed to examine the role of extracellular and...