A fast and automated solution for accurately resolving protein domain architectures
Abstract
Accurate prediction of the domain content and arrangement in multi-domain proteins (which make up >65% of the large-scale protein databases) provides a valuable tool for function prediction, comparative genomics and studies of molecular evolution. However, scanning a multi-domain protein against a database of domain sequence profiles can often produce conflicting and overlapping matches. We have developed a novel method that employs heaviest...
Paper Details
Title
A fast and automated solution for accurately resolving protein domain architectures
Published Date
Jan 29, 2010
Journal
Volume
26
Issue
6
Pages
745 - 751
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