Construction and validation of the APOCHIP, a spotted oligo-microarray for the study of beta-cell apoptosis

Volume: 6, Issue: 1
Published: Dec 1, 2005
Abstract
Background Type 1 diabetes mellitus (T1DM) is a autoimmune disease caused by a long-term negative balance between immune-mediated beta-cell damage and beta-cell repair/regeneration. Following immune-mediated damage the beta-cell fate depends on several genes up- or down-regulated in parallel and/or sequentially. Based on the information obtained by the analysis of several microarray experiments of beta-cells exposed to pro-apoptotic conditions...
Paper Details
Title
Construction and validation of the APOCHIP, a spotted oligo-microarray for the study of beta-cell apoptosis
Published Date
Dec 1, 2005
Volume
6
Issue
1
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