Expression of Markers of Platelet Activation and the Interpatient Variation in Response to Abciximab

Volume: 19, Issue: 2, Pages: 212 - 219
Published: Feb 1, 1999
Abstract
—Our study concerns the biological effects of abciximab (c7E3 Fab, ReoPro), a powerful new antiplatelet drug that blocks glycoprotein (GP) IIb-IIIa complexes. Samples were examined from 6 patients with coronary artery disease who received a bolus of abciximab followed by a 10-μg/min infusion for at least 18 hours before percutaneous transluminal coronary angioplasty. Inhibition of ADP-induced PA was maximal for 4 patients but partial (79% and...
Paper Details
Title
Expression of Markers of Platelet Activation and the Interpatient Variation in Response to Abciximab
Published Date
Feb 1, 1999
Volume
19
Issue
2
Pages
212 - 219
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