Effect of Valsartan on Systemic Right Ventricular Function

The role of angiotensin II receptor blockers in patients with a systemic right ventricle has not been elucidated.We conducted a multicenter, double-blind, parallel, randomized controlled trial of angiotensin II receptor blocker valsartan 160 mg twice daily compared with placebo in patients with a systemic right ventricle caused by congenitally or surgically corrected transposition of the great arteries. The primary end point was change in right...