Expectation and Dopamine Release: Mechanism of the Placebo Effect in Parkinson's Disease
Abstract
The power of placebos has long been recognized for improving numerous medical conditions such as Parkinson's disease (PD). Little is known, however, about the mechanism underlying the placebo effect. Using the ability of endogenous dopamine to compete for [11C]raclopride binding as measured by positron emission tomography, we provide in vivo evidence for substantial release of endogenous dopamine in the striatum of PD patients in response to...
Paper Details
Title
Expectation and Dopamine Release: Mechanism of the Placebo Effect in Parkinson's Disease
Published Date
Aug 10, 2001
Journal
Volume
293
Issue
5532
Pages
1164 - 1166
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