Aging and Survival: The Genetics of Life Span Extension by Dietary Restriction
Abstract
Reducing food intake to induce undernutrition but not malnutrition extends the life spans of multiple species, ranging from single-celled organisms to mammals. This increase in longevity by dietary restriction (DR) is coupled to profound beneficial effects on age-related pathology. Historically, much of the work on DR has been undertaken using rodent models, and 70 years of research has revealed much about the physiological changes DR induces....
Paper Details
Title
Aging and Survival: The Genetics of Life Span Extension by Dietary Restriction
Published Date
Jun 1, 2008
Volume
77
Issue
1
Pages
727 - 754
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Notes
History