Neuropeptide Y contributes to innervation-dependent increase in I(Ca, L) via ventricular Y2 receptors.

Volume: 277, Issue: 3
Published: Sep 1, 1999
Abstract
The developmental increase in L-type Ca current (I(Ca,L)) density in the rat ventricle is reproduced in vitro by culturing neonatal myocytes with sympathetic neurons. We tested whether this effect of sympathetic innervation results from a chronic or sustained action of neurally released neuropeptide Y (NPY). Ventricular myocytes from newborn rats were cultured in serum-free medium with or without sympathetic neurons, NPY, or NPY analogs. Ca...
Paper Details
Title
Neuropeptide Y contributes to innervation-dependent increase in I(Ca, L) via ventricular Y2 receptors.
Published Date
Sep 1, 1999
Volume
277
Issue
3
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