Immunogenic Cell Death in Cancer Therapy
Abstract
Depending on the initiating stimulus, cancer cell death can be immunogenic or nonimmunogenic. Immunogenic cell death (ICD) involves changes in the composition of the cell surface as well as the release of soluble mediators, occurring in a defined temporal sequence. Such signals operate on a series of receptors expressed by dendritic cells to stimulate the presentation of tumor antigens to T cells. We postulate that ICD constitutes a prominent...
Paper Details
Title
Immunogenic Cell Death in Cancer Therapy
Published Date
Mar 21, 2013
Journal
Volume
31
Issue
1
Pages
51 - 72
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