The effect of poloxamer 188 on nanoparticle morphology, size, cancer cell uptake, and cytotoxicity

Volume: 6, Issue: 1, Pages: 170 - 178
Published: Feb 1, 2010
Abstract
null null The aim of this work was to investigate the effect of triblock copolymer poloxamer 188 on nanoparticle morphology, size, cancer cell uptake, and cytotoxicity. Docetaxel-loaded nanoparticles were prepared by oil-in-water emulsion/solvent evaporation technique using biodegradable poly(lactic-co-glycolic acid) (PLGA) with or without addition of poloxamer 188, respectively. The resulting nanoparticles were found to be spherical with a...
Paper Details
Title
The effect of poloxamer 188 on nanoparticle morphology, size, cancer cell uptake, and cytotoxicity
Published Date
Feb 1, 2010
Volume
6
Issue
1
Pages
170 - 178
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