Role of Growth Arrest–Specific Gene 6 in the Development of Fungal Allergic Airway Disease in Mice

Volume: 51, Issue: 5, Pages: 615 - 625
Published: Nov 1, 2014
Abstract
Growth arrest-specific gene (Gas)6 is a secreted vitamin K-dependent protein with pleiotropic effects via activation of receptor tyrosine kinase Tyro3, Axl, and Mertk receptors, but little is known about its role in allergic airway disease. We investigated the role of Gas6 in the development of fungal allergic airway disease in mice. The immune response was evaluated in Gas6-deficient (Gas6-/-) and wild-type (WT) mice and in recombinant...
Paper Details
Title
Role of Growth Arrest–Specific Gene 6 in the Development of Fungal Allergic Airway Disease in Mice
Published Date
Nov 1, 2014
Volume
51
Issue
5
Pages
615 - 625
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