7C3, A Marker for the Differentiation of Human Macrophage Cell Lines

Volume: 42, Issue: 5, Pages: 491 - 497
Published: Nov 1, 1987
Abstract
The induction of differentiation in the human monoblastlike cell line U937 by 1,25 dihydroxyvitamin D3, interferon gamma, or phorbol esters is associated with the expression of a novel surface antigen, 7C3. The expression of 7C3 is maximal after 24 hr and is dependent upon de novo protein synthesis. The appearance of 7C3 during U937 differentiation is inhibited by dexamethasone while the increased expression of the macrophage marker OKM1 is not...
Paper Details
Title
7C3, A Marker for the Differentiation of Human Macrophage Cell Lines
Published Date
Nov 1, 1987
Volume
42
Issue
5
Pages
491 - 497
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