Randomised controlled trial of faecal-occult-blood screening for colorectal cancer

There is growing evidence that faecal-occult-blood (FOB) screening may reduce colorectal cancer (CRC) mortality, but this reduction in CRC mortality has not been shown in an unselected population-based randomised controlled trial. The aim of this study was to assess the effect of FOB screening on CRC mortality in such a setting.Between February, 1981, and January, 1991, 152,850 people aged 45-74 years who lived in the Nottingham area of the UK...