The new biology of aldosterone
Abstract
Classically, aldosterone is synthesised in the adrenal zona glomerulosa and binds to specific mineralocorticoid receptors located in the cytosol of target epithelial cells. Translocation of the resulting steroid receptor complex to the cell nucleus modulates gene expression and translation of specific 'aldosterone-induced' proteins that regulate electrolyte and fluid balance. However, non-epithelial and rapid non-genomic actions of aldosterone...
Paper Details
Title
The new biology of aldosterone
Published Date
Jul 1, 2005
Journal
Volume
186
Issue
1
Pages
1 - 20
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