Postoperative Radiation Therapy for Pathologically Advanced Prostate Cancer After Radical Prostatectomy

Approximately 15–25% of men who undergo radical prostatectomy for localized prostate cancer (PCa) will experience recurrence of their cancer; men with poorly differentiated cancer, non–organ-confined disease, and positive surgical margins are at the highest risk. Review accumulating evidence indicating that postoperative radiotherapy (RT) to the prostate bed favorably influences the course of disease in men with adverse pathologic features....