Role of Nanofibrous Poly(Caprolactone) Scaffolds in Human Mesenchymal Stem Cell Attachment and Spreading forIn VitroBone Tissue Engineering—Response to Osteogenic Regulators

In this study, we evaluated the role of fiber size scale in the adhesion and spreading potential of human mesenchymal stem cells (hMSCs) on electrospun poly(caprolactone) (PCL) nanofibrous and microfibrous scaffolds. The effect of in vivo regulators in inducing osteogenic differentiation of hMSCs on PCL nanofibrous scaffolds was investigated using osteogenic differentiation marker gene expression and matrix mineralization. Here, we report for...