Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease

Nature64.80
Volume: 472, Issue: 7341, Pages: 57 - 63
Published: Apr 7, 2011
Abstract
Metabolomics studies hold promise for the discovery of pathways linked to disease processes. Cardiovascular disease (CVD) represents the leading cause of death and morbidity worldwide. Here we used a metabolomics approach to generate unbiased small-molecule metabolic profiles in plasma that predict risk for CVD. Three metabolites of the dietary lipid phosphatidylcholine—choline, trimethylamine N-oxide (TMAO) and betaine—were identified and then...
Paper Details
Title
Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease
Published Date
Apr 7, 2011
Journal
Volume
472
Issue
7341
Pages
57 - 63
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