Venus trap in the mouse embryo reveals distinct molecular dynamics underlying specification of first embryonic lineages
Abstract
Mammalian development begins with the segregation of embryonic and extra-embryonic lineages in the blastocyst. Recent studies revealed cell-to-cell gene expression heterogeneity and dynamic cell rearrangements during mouse blastocyst formation. Thus, mechanistic understanding of lineage specification requires quantitative description of gene expression dynamics at a single-cell resolution in living embryos. However, only a few fluorescent gene...
Paper Details
Title
Venus trap in the mouse embryo reveals distinct molecular dynamics underlying specification of first embryonic lineages
Published Date
Jul 3, 2015
Journal
Volume
16
Issue
8
Pages
1005 - 1021
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Notes
History