Psychopharmacology and adverse effects of antipsychotic long-acting injections: A review

Background Depot antipsychotics are widely used in clinical practice. Long-acting formulations of second-generation antipsychotics are now being developed and introduced. Aims To review the pharmacology, pharmacokinetics and adverse effect profiles of currently available antipsychotic long-acting injections (LAIs). Method The psychopharmacological properties of first- and second-generation antipsychotic LAIs are reviewed using data available up...