Infliximab-induced retrobulbar optic neuritis

A 51-year-old woman underwent four cycles of intravenous infliximab for refractory active ulcerative colitis diagnosed 15 years earlier. She had a 1-month history of fever, abdominal pain and bloody diarrhoea, findings consistent with a relapse of her disease. She was also taking oral mesalazine, prednisone and azathioprine. Three weeks later, during the last cycle of infliximab, she developed pain, blurred vision and a loss in the visual field...