RNA sequencing-based identification of aberrant imprinting in cloned mice

Volume: 23, Issue: 4, Pages: 992 - 1001
Published: Feb 15, 2014
Abstract
Animals cloned by somatic cell nuclear transfer (SCNT) provide a unique model for understanding the mechanisms of nuclear epigenetic reprogramming to a state of totipotency. Though many phenotypic abnormalities have been demonstrated in cloned animals, the underlying mechanisms are not well understood. In this study, we performed transcriptome-wide allelic expression analyses in brain and placental tissues of cloned mice. We found that Gab1,...
Paper Details
Title
RNA sequencing-based identification of aberrant imprinting in cloned mice
Published Date
Feb 15, 2014
Volume
23
Issue
4
Pages
992 - 1001
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