The Two Faces of Interferon-γ in Cancer
Abstract
Interferon-γ is a cytokine whose biological activity is conventionally associated with cytostatic/cytotoxic and antitumor mechanisms during cell-mediated adaptive immune response. It has been used clinically to treat a variety of malignancies, albeit with mixed results and side effects that can be severe. Despite ample evidence implicating a role for IFN-γ in tumor immune surveillance, a steady flow of reports has suggested that it may also have...
Paper Details
Title
The Two Faces of Interferon-γ in Cancer
Published Date
Oct 1, 2011
Journal
Volume
17
Issue
19
Pages
6118 - 6124
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