Tumour vascularization via endothelial differentiation of glioblastoma stem-like cells
Abstract
Glioblastoma is a highly angiogenetic malignancy, the neoformed vessels of which are thought to arise by sprouting of pre-existing brain capillaries. The recent demonstration that a population of glioblastoma stem-like cells (GSCs) maintains glioblastomas indicates that the progeny of these cells may not be confined to the neural lineage. Normal neural stem cells are able to differentiate into functional endothelial cells. The connection between...
Paper Details
Title
Tumour vascularization via endothelial differentiation of glioblastoma stem-like cells
Published Date
Sep 8, 2011
Journal
Volume
468
Issue
7325
Pages
824 - 828
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