HLA-B*5701 Screening for Hypersensitivity to Abacavir

Volume: 358, Issue: 6, Pages: 568 - 579
Published: Feb 7, 2008
Abstract
Hypersensitivity reaction to abacavir is strongly associated with the presence of the HLA-B*5701 allele. This study was designed to establish the effectiveness of prospective HLA-B*5701 screening to prevent the hypersensitivity reaction to abacavir. Methods This double-blind, prospective, randomized study involved 1956 patients from 19 countries, who were infected with human immunodeficiency virus type 1 and who had not previously received...
Paper Details
Title
HLA-B*5701 Screening for Hypersensitivity to Abacavir
Published Date
Feb 7, 2008
Volume
358
Issue
6
Pages
568 - 579
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