Plasmablast frequency and trafficking receptor expression are altered in pediatric ulcerative colitis
Abstract
The incidence of pediatric ulcerative colitis (UC), a chronic autoinflammatory disease of the colon, is on the rise. Although an increased infiltration of B cells from the peripheral blood into the colon occurs in UC, B-cell trafficking is understudied. We hypothesized that the frequency of circulating plasmablasts (PBs) and their trafficking receptor (TR) expression may be indicative of the location and degree of pathology in pediatric UC.We...
Paper Details
Title
Plasmablast frequency and trafficking receptor expression are altered in pediatric ulcerative colitis
Published Date
Dec 1, 2012
Journal
Volume
18
Issue
12
Pages
2381 - 2391
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