Thioredoxin Reductase and its Inhibitors
Abstract
Thioredoxin plays a crucial role in a wide number of physiological processes, which span from reduction of nucleotides to deoxyriboucleotides to the detoxification from xenobiotics, oxidants and radicals. The redox function of Thioredoxin is critically dependent on the enzyme Thioredoxin NADPH Reductase (TrxR). In view of its indirect involvement in the above mentioned physio/pathological processes, inhibition of TrxR is an important clinical...
Paper Details
Title
Thioredoxin Reductase and its Inhibitors
Published Date
May 29, 2014
Volume
15
Issue
6
Pages
621 - 646
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