Colorectal carcinoma: Importance of colonic environment for anti-cancer response and systemic immunity
Abstract
The intestinal environment is considered to play an important role both in colorectal tumor development and in the evolution and modulation of mucosal immunity. Studies in animals reared in germ-free (GF, without any intestinal microflora) versus conventional (CV, with regular microflora in bowel) conditions can aid in clarifying the influence of bacteria on carcinogenesis and anti-cancer immune responses in situ. The lower incidence of colon...
Paper Details
Title
Colorectal carcinoma: Importance of colonic environment for anti-cancer response and systemic immunity
Published Date
Nov 12, 2009
Journal
Volume
6
Issue
4
Pages
217 - 226
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History