Evaluation of the photooxidation of galactosyl‐ and lactosylceramide by electrospray ionization mass spectrometry

Glycosphingolipids are important lipid molecules namely as constituents of the plasma membrane organized in lipid rafts, in signal transduction, and cell-cell communication. Although many human diseases are associated with oxidative stress and lipid oxidation, a link between oxidative stress and modification of glycosphingolipids has never been addressed.In this study, the structural changes caused by UVA-induced photooxidation of galactosyl-...