A Uniform System for the Annotation of Vertebrate microRNA Genes and the Evolution of the Human microRNAome
Abstract
Although microRNAs (miRNAs) are among the most intensively studied molecules of the past 20 years, determining what is and what is not a miRNA has not been straightforward. Here, we present a uniform system for the annotation and nomenclature of miRNA genes. We show that less than a third of the 1,881 human miRBase entries, and only approximately 16% of the 7,095 metazoan miRBase entries, are robustly supported as miRNA genes. Furthermore, we...
Paper Details
Title
A Uniform System for the Annotation of Vertebrate microRNA Genes and the Evolution of the Human microRNAome
Published Date
Nov 23, 2015
Journal
Volume
49
Issue
1
Pages
213 - 242
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