High expression of ZNF703 independent of amplification indicates worse prognosis in patients with luminal B breast cancer

Amplification of 8p12‐p11 is relatively common in breast cancer and several genes within the region have been suggested to affect breast tumor progression. The aim of the study was to map the amplified 8p12‐p11 region in a large set of breast tumors in an effort to identify the genetic driver and to explore its impact on tumor progression and prognosis. Copy number alterations ( CNA s) were mapped in 359 tumors, and gene expression data from 577...