Complex trait analysis of gene expression uncovers polygenic and pleiotropic networks that modulate nervous system function

Volume: 37, Issue: 3, Pages: 233 - 242
Published: Feb 13, 2005
Abstract
Patterns of gene expression in the central nervous system are highly variable and heritable. This genetic variation among normal individuals leads to considerable structural, functional and behavioral differences. We devised a general approach to dissect genetic networks systematically across biological scale, from base pairs to behavior, using a reference population of recombinant inbred strains. We profiled gene expression using Affymetrix...
Paper Details
Title
Complex trait analysis of gene expression uncovers polygenic and pleiotropic networks that modulate nervous system function
Published Date
Feb 13, 2005
Volume
37
Issue
3
Pages
233 - 242
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