Identification of a Functional Antioxidant Response Element within the Eighth Intron of the Human ABCC3 Gene
Abstract
The ATP-binding cassette (ABC) family of transporters, including ABCC3, is a large family of efflux pumps that plays a pivotal role in the elimination of xenobiotics from the body. ABCC3 has been reported to be induced during hepatic stress conditions and through the progression of some forms of cancer. Several lines of evidence have implicated the transcription factor nuclear factor (erythroid-derived 2)-like 2 (Nrf2) in this induction....
Paper Details
Title
Identification of a Functional Antioxidant Response Element within the Eighth Intron of the Human ABCC3 Gene
Published Date
Oct 27, 2014
Volume
43
Issue
1
Pages
93 - 99
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