Clinical safety of the selective PKC-β inhibitor, ruboxistaurin
Abstract
The aim of this manuscript is to report the safety profile of patients treated with ruboxistaurin mesylate (RBX; LY333531), a selective protein kinase C-beta (PKC-beta) inhibitor, for up to 4 years. Data from patients with diabetes (1396 RBX 32 mg/day; 1408 placebo) were combined from 11 placebo-controlled, double-masked studies. The proportion of patients who reported one or more serious adverse events was greater in the placebo group than in...
Paper Details
Title
Clinical safety of the selective PKC-β inhibitor, ruboxistaurin
Published Date
Oct 18, 2006
Volume
5
Issue
6
Pages
835 - 845
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